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Table of Contents | 2025
Nighttime Urination and Sleep Apnea: The Overlooked Connection
Jordan Robertson, ND Understanding the link between nocturia and obstructive sleep apnea (OSA) can improve screening and treatment outcomes, especially in women. Key Takeaways Patients with nocturia have an increased risk of obstructive sleep apnea (OSA) and may...
Bridging the Gap: Psychedelic Medicine and the Holistic Model in Psychiatry
Suzanne Blaising, PhD, Mary Rondeau, ND Exploring how psychedelic therapy, particularly psilocybin, enhances holistic mental health care by promoting neuroplasticity, emotional breakthroughs, and sustainable recovery. Introduction: The conventional mental health care...
Resolving Acne Vulgaris Through Gut and Hormone Support: A Case Study
By Chelsea Smithback, ND Introduction Acne vulgaris is a very common skin condition, with a prevalence rate ranging from 25% to 95% among adolescents. It is more common in males than females. Acne can persist into adulthood or have a delayed onset during this stage of...
Targeting Menopausal Acne: Hormone Balancing and Skin Barrier Support in Practice
Aarti Patel, ND ABSTRACT This case study explores menopausal acne in a 55-year-old female with severe skin barrier damage from a history of using medical-grade prescription, as well as over-the-counter acne topicals, along with a more recent history of supplementing...
Mechanisms of Aging and Neurodegeneration
Exploring Thiamine Deficiency, Catecholamine Toxicity, and Angiotensin II Quinn Rivet, ND Exploring how thiamine deficiency, catecholamine-induced neurotoxicity, and Angiotensin II contribute to neurodegeneration and aging in the brain. Introduction This paper aims to...
Breaking the Cycle: Understanding PCOS-Related Skin Manifestations
Pathophysiology, Clinical Implications, and Evidence-Based Naturopathic Interventions Galina Mironova, ND Polycystic Ovarian Syndrome (PCOS) is a complex endocrine disorder with systemic effects, including significant dermatologic manifestations. Acne, hirsutism,...
From Pain to Relief: A Shingles Victory with Homeopathy
Michael Knapp, ND, DHANP How a 51-Year-Old Female Achieved Fast Relief from Shingles Using Classical Homeopathy Abstract This case illustrates the successful treatment of shingles with individualized homœpathic medicine in a 51-year-old female. The outcome is...
Geriatric Syndrome—Bone Up, Muscle Up, and More with Myostatin Inhibition
Chris D. Meletis, N.D. How Myostatin Inhibition Supports Bone Density, Prevents Sarcopenia, and Enhances Musculoskeletal Health in Aging Populations Osteoporosis and sarcopenia are major concerns for aging individuals, often leading to fractures and loss of...
Topical Treatments for Rosacea: A Clinical Comparison of Efficacy and Patient Outcomes
Jordan Robertson, ND A detailed evaluation of the most commonly prescribed topical treatments for rosacea, comparing efficacy, patient suitability, and clinical outcomes. Rosacea significantly affects patients' quality of life, and evidence indicates that any...
Mental Health & Insomnia – May 2025 | Volume 20 | Issue 5
Issue Details Volume 20 | Issue No.05Published: May 2025Theme: Mental Health and InsomniaISSN: 2169-1622 [simplebooklet src="https://simplebooklet.com/embed.php?wpKey=xbnZ815tnZmF3SIlTBBI6f&source=wordpress" width="100%" height="637"]
Occupationally Exacerbated Palmoplantar Dermatitis with Systemic Triggers
Carrie Phillips, ND Introduction As naturopathic physicians, we recognize that medicine is both an art and a science. It requires clinical reasoning, empirical evidence, and intuition that comes from experience. This balance is reflected in our practice, which is a...
The Integrative Management of Psoriasis
A Case Study in Homeopathy, Nutrition, and Lifestyle Medicine A comprehensive, patient-centered approach to managing psoriasis by addressing root causes through homeopathy, gut health, and metabolic balance. By Marisa Kassimir, ND Introduction and Case Presentation...
Optimizing Healthy Aging for Older Adults
Insights from a Case Series Using a Novel Supplement Regimen Jen Palmer, ND; Joseph M. Keenan, MD Dietary supplements can provide older adults a therapeutic option for maintaining optimal health without relying on prescription drugs. This article summarizes key...
From Kitty Litter to Cortical Recovery
A Naturopathic Case Study on Reversing CIRS-Induced Brain Atrophy Eric Dorninger ND, LAc This case study examines a 39-year-old male with severe neurological symptoms linked to Chronic Inflammatory Response Syndrome (CIRS) triggered by endotoxin exposure from a kitty...
From Toxicology to Clinical Application:
Applying Primary Source Research to Homeopathic Practice Jamie Oskin, ND, DTBRm, DHANP In a previous NDNR editorial, I gave a review of a groundbreaking new conference at Sonoran University in Tempe, Arizona, that was a collaborative project of the American Institute...
Archived Case Studies and Featured Content
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Integrative Treatment of PCOS, Endometriosis, and Perimenopause: Addressing the Hormone-Inflammation Cycle
Dr. Pamela Frank, BSc (Hons), ND Polycystic ovary syndrome (PCOS) was renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 through an international consensus published in The Lancet. The new name reflects the hormonal, metabolic, and systemic...
Naturopathic Support for Age-Related eGFR Decline: A Clinical Guide
Dr. Jenna Henderson, ND A clinical overview of kidney function changes with aging, common diagnostic pitfalls, and natural approaches to support renal health in older adults. Short Description This article examines the natural decline in kidney function...
Naturopathic Approach to Women’s Hormone Health: From Menarche to Menopause
Dr. Serena Goldstein, ND A comprehensive review of hormonal changes, mood, metabolism, and integrative strategies to support women’s health at every life stage. Short Description This article explores hormonal changes across the female lifespan—from menarche...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
A Naturopathic Detox from the COVID Era: Healing the Profession Through Truth and Compassion
Charley Cropley, N.D Abstract A reflective exploration of professional conflict within naturopathic medicine and a vitalist framework for restoring integrity, dialogue, and collective healing. This commentary examines the impact of the COVID era on the...
Why Naturopathic Doctors Recommend Different Treatments: Understanding Individualized Care in Naturopathic Medicine
Dr. Eli Camp, ND How vitalist principles, clinical judgment, and therapeutic order shape personalized treatment strategies for the same diagnosis. Abstract This article explains why two naturopathic doctors may recommend different treatments for the same...
Curcumin Benefits and Bioavailability: Separating Mechanism from Marketing
Devin Miles, ND Abstract This article reviews the clinical evidence supporting curcumin’s role in inflammation, joint health, and oxidative stress, including comparisons with conventional therapies such as NSAIDs. It also examines the challenges of curcumin...
GLP-1 Agonists and Persistent Organic Pollutants (POPs): Lipophilic Toxin Mobilization During Rapid Fat Loss
Michael E. McEvoy, Kareem Kandil, ND This article examines the potential for rapid fat loss induced by GLP-1 agonist therapies to mobilize stored lipophilic persistent organic pollutants (POPs) from adipose tissue into circulation. It reviews evidence from weight loss...
Paris to Host Landmark Global Gathering for Naturopathic Medicine in 2026
10th Integrative & Naturopathic Medicine World Congress & Expo Returns for Its Milestone 10th Edition Paris — July 10–11, 2026 — The global stage is set for one of the most influential events in integrative healthcare as the 10th Integrative &...
Restorative Formulations Launches the NeuroSynergy Clinical Series
Four professional-grade formulas targeting distinct neurochemical pathways to support mood, stress resilience, and cognitive function are now available exclusively to licensed practitioners. Montpelier, VT, March 27, 2026 — Restorative Formulations has released the...
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Featured News
Three Endocrine Axes Share One Energy Budget for Stress Resilience
Three Endocrine Axes Share One Energy Budget for Stress Resilience Mitochondrial reserve capacity constrains the HPA, thyroid, and gonadal systems simultaneously, determining whether stress responses stay adaptive or consolidate into chronic dysfunction. When a...
AANP and AANMC Urge Naturopathic Community to Act: Proposed Federal Rule Threatens ND Student Loan Access and Future Workforce
Washington, DC — The American Association of Naturopathic Physicians (AANP) and the Association of Accredited Naturopathic Medical Colleges (AANMC) are calling on naturopathic physicians, students, patients, and all allies to urgently submit public comments opposing a...
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