Understanding the impact of bone turnover on heavy metal toxicity and how to manage chelation therapy safely. By Paul Anderson Acute and ongoing exposures should be assessed and identified to the degree possible before starting heavy metal chelation. Sources of acute...
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Table of Contents | 2025
Homotoxicology—A Revolutionary Approach to Understanding and Reversing Chronic Disease
By Mark Iwanicki Exploring how toxin bioaccumulation drives chronic illness and how homotoxicology provides a systematic framework for detoxification, ECM restoration, and long-term healing Chronic disease is the defining health challenge of our era, with conditions...
The (Not So) Hidden Health Effects of Fast Fashion
Unveiling the Environmental and Health Costs of Trendy, Affordable Clothing By Nozomi Gonzalez, ND Introduction We live in one of the trendiest times in history. Trends in fashion have existed almost as long as humans have worn clothes, but for most of the past, only...
Co-Treating Asthma Patients with Supplements
Evidence for Combination Therapy By Jordan Robertson This article reviews the evidence supporting the integration of nutritional supplements, such as vitamin D, magnesium, and fish oil, in asthma management. Learn how naturopathic approaches can enhance control and...
Homeopathic Management: Acute, Subacute, and Chronic Coughs
By Sharum Sharif, ND Abstract Homeopathy offers effective management for acute, subacute, and chronic coughs, particularly those arising from infectious and post-infectious conditions. By prioritizing etiology, characteristic symptoms, and the nature of the cough—such...
In the Thick of It: Diagnosis and Treatment for Venous Form of Thoracic Outlet Syndrome with Comorbid Tick-Borne Infections
Julia Greenspan, ND Abstract This case report details the diagnosis and management of venous thoracic outlet syndrome with concurrent tick-borne infections, emphasizing diagnostic pitfalls, the utility of D-dimer with imaging, and timely interventions including...
A Spin on Crataegus: East vs. West View on the Quintessential Heart Health Herb
By Heather Tynan, ND If you know herbs and heart health, you know hawthorn (Crataegus spp). This plant is well known for its gentle yet powerful tonification effects on the heart and the entire cardiovascular system, notably its ability to moderately lower blood...
Understanding Preeclampsia
How to Reduce Risk in Pregnancy and Prevent Future Cardiovascular Disease By Alexsia Priolo Introduction Pregnancy places significant physiologic stress on the cardiovascular system, prompting structural and hemodynamic changes to manage increased blood volume and...
Adjunctive Treatment of Paroxysmal Atrial Fibrillation
Botanical and Nutrient Therapies By Alexandra Mele, ND This article explores the case of a 76-year-old patient with treatment-resistant paroxysmal atrial fibrillation. It highlights how botanical medicines and nutrient therapies complement conventional care, including...
Allergy / Immunology / Environmental / Toxicology Issues – March 2025 | Volume 20 | Issue 2
Issue Details Volume 20 | Issue No.01Published: Jan 2025Theme: Women’s HealthISSN: 2169-1622 [simplebooklet src="https://simplebooklet.com/embed.php?wpKey=TfHb8yHXoODbAWSBz3m4Ju&source=wordpress" width="986" height="637"] We are excited to present the official...
The Case of the Man with “Unmasked” Premature Ventricular Contractions
A Case Study By Michael Knapp, ND, DHANP This case study examines the treatment journey of a 72-year-old male with premature ventricular contractions (PVCs) following atrial fibrillation ablation. The article highlights the use of Natrum muriaticum, homeopathic...
Announcing a New Online Digital Library of Primary Sources Unveiled at a Recent Conference
By Jamie Oskin, ND, DTBRm, DHANP This past September 20-22, 2024, we hosted a groundbreaking new conference at Sonoran University in Tempe, Arizona, that was a collaborative project of the American Institute of Homœopathy (AIH), Homœopathic Academy of Naturopathic...
Integrating BioIdentical Hormones and Herbal Protocols
Naturopathic Clinical Pearls By Jannine Krause, ND Hormone Replacement Therapy (HRT) and Bio-Identical HRT (Bio-HRT) are often debated in the medical community, leaving many women confused about their options. This article explores a naturopathic approach that...
Differentiating Perimenopause: Avoiding Diagnostic Pitfalls
By Thara Vayali, ND Exploring the complexities of perimenopause, its clinical challenges, and how naturopathic physicians can differentiate symptoms and address root causes. This article delves into the nuances of perimenopause, outlining its stages, associated...
Autoimmunity, Women, and Relationship to Self
Delve into cultural, emotional, and physiological triggers for self-healing By Nicola Dehlinger, ND Exploring the unique connection between autoimmunity and women’s health, delving into cultural, emotional, and physiological triggers for self-healing. This article...
Archived Case Studies and Featured Content
Quantum Fields and Frequency Medicine
RAZI BERRY Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Epstein–Barr Virus (EBV) as a Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
The Fertility Factor No One Talks About: Men’s Energetic Health
Dr. Laura Chan, ND, L.Ac. While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...
Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
Mind, Immunity & Male Fertility: A Psychoneuroimmunological View of Male Reproductive Health
Dr. Nicole Cain Exploring how chronic stress, inflammation, and the gut-brain-hormone connection influence sperm quality—and how integrative, mind-body interventions can restore reproductive vitality in men. Abstract This article examines male infertility...
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
The Quiet Surge in Demand for Psychiatric Drug Tapering
Razi Ann Berry, Publisher We Became a Medicated Society More than one in ten American adults now take prescription medication for depression. Women receive these prescriptions at double the rate of men. Add in antipsychotics, stimulants, mood stabilizers, and...
Metagenics Names Patrick Sly as CEO to Lead Next Chapter of Growth
Aliso Viejo, CA – December 1, 2025 Metagenics, a leading doctor-recommended professional supplement announced it has named Patrick Sly as CEO, effective immediately. A highly regarded executive in the health and wellness industry, Mr. Sly brings a wealth of...
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
Brazilian Copper Chelation Study Puts Numbers Behind What We’ve Been Testing For
A new compound reduced hippocampal inflammation and improved memory in Alzheimer's model rats A research team in Brazil has published animal data showing a copper chelating compound can cross the blood brain barrier, pull copper out of beta amyloid plaques, and...
A Publisher’s Warning: The Pediatric Cases That Cross My Desk 20 Years Later
Razi Ann Berry, Publisher When we started publishing cases in the Journal of Applied Naturopathic Medicine (formerly NDNR), the bulk of pediatric cases were mild: ear infections, upper respiratory infections, rashes, food allergies. Parents who brought their...
Gentle
Razi Ann Berry, Publisher Why Starting Gentle Is Actually Radical The order you do things matters. When baking bread, repairing an engine, building a house; do it out of order and it fails. In medicine, we’ve reversed the order. We start with the strongest...
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Featured News
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
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