ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
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Trending Articles
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Eight Communities You Never Thought of That Can Be a Goldmine for Finding New Patients
Advancing Public Health Through Community Alignment Valuing self-reliance and freedom, certain enthusiast groups are naturally drawn to holistic, naturopathic, and integrative care because it aligns with their ethos of personal autonomy and preparedness. These are...
Overcoming Objections to Pay Cash for Doctor’s Visits: Scripts Your Staff Can Use
Razi Berry Handling Objections Handling objections to paying cash for doctor’s visits can be a delicate task. It requires empathy, clear communication, and an understanding of the patient's concerns. Here are some effective scripts that your staff can use to address...
Fifteen Questions to Get Patient Commitment
Razi Berry A practical tool for doctors, practice managers, and staff to support patient decision-making and follow-through Practitioners often say they do not want to be salespeople. In practice, sales are simply a decision and a transaction between two people. One...
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Featured Article | Anti-Aging
Gene Links Stress Response and Learning Disabilities
From Duke University A gene that has been associated with severe learning disabilities in humans has been found to also play a vital role in cells' response to environmental stress, according to a Duke University study appearing May 24 in the journal Cell Reports....
Exclusive Content | Anti-Aging
Ayurvedic Approaches to Prevent and Manage Alzheimer Disease
Rasayana herbs, sattvic food choices, and panchakram therapies Virender Sodhi, MD (Ayurveda), ND Teresa Goldsmith, ND, AWP Alzheimer disease (AD) is a neuro-degenerative disease that affects more than 4 million Americans.1 It is considered an irreversible disorder...
A Long Perspective on Longevity: Antiaging and “Inflammaging”
Jillian Stansbury, ND Over the many millennia of humanity’s evolution, the average life expectancy has increased substantially, from well under 30 years in Paleolithic times to about a world average of 67 years at present. There are striking differences in the average...
Beyond Sunscreen: Skin Chemoprotection With Natural Medicine
Heather Paulson, ND; Betsy Rice, ND The skin is the largest organ of our body and is an important interface between our other organs and the outside environment. Observing the skin can be a window into the internal function of a patient’s body. Most skin disorders are...
Update on Trends, Safety, and Efficacy in Dermatology
Lisa Meserole, MS, ND Antiaging treatments for skin and beauty are skyrocketing. The science and research of dermatology and the skin have advanced dramatically. Innovations in formulation through new technologies offer increased functional effects in hair and skin...
Antiaging Facial Acupuncture
Jennifer Hillier, ND A 54-year-old woman was seen at the clinic with reports of fatigue and shortness of breath on exertion following an episode of pneumonia 2 months earlier. Further questioning revealed a history of irritable bowel syndrome, the recent need for...
Aesthetic Use for Platelet-Rich Plasma
An Innovative Addition to the Clinical Toolbox Michael Rahman, BSc, ND The human body has a remarkable capacity to heal itself. Regeneration of new tissue is accomplished by stem cells and is fostered by growth factors and hormones. Platelet-rich plasma (PRP) is an...
Walking a Tightrope
Joseph Kellerstein, DC, ND I just got off the phone with a lovely lady whom I had not spoken to for about a year since our previous appointment. The result was so striking to me in the way of a good teaching point that I wanted to share my learning with all of you....
Recalcitrant Bilateral Osteoarthritis
Case Study of a 63-Year-Old Man Bryan Rade, ND HH, a 63-year-old man, presented to the office with a 2-year history of worsening bilateral, radiographically confirmed, osteoarthritis (OA) of the thumbs. The pain had a rapid onset over a 6-month period to an intensity...
Archived Case Studies and Featured Content
Rebuilding the Brain in Chronic Fatigue Syndrome (CFS/ME): A Layered Naturopathic Approach to Neuroinflammation and Mitochondrial Dysfunction
A case report demonstrating sequential neurorepair, lipid repletion, microbiome stabilization, and mitochondrial support in post-infectious CFS/ME recovery. Dr. Vy Simeles, ND, Restorative Health Clinic Abstract This case report details the recovery of a 22-year-old...
Infection, Neuroinflammation, and Immune Dysregulation: The Clinical Overlap of Lyme Disease and PANS/PANDAS and a Path to Healing
Understanding the clinical overlap between vector-borne infections and pediatric acute-onset neuropsychiatric syndromes—and a systems-based integrative path to healing. Dr. Myriah Hinchey, ND, FMAPS Abstract This article examines the biological overlap between Lyme...
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Dr. Chris D Meletis Oxaloacetate: A Missing Link in CFS, Long-Haul COVID, and Mitochondrial Performance
Psudoscience
Razi Ann Berry, Publisher After 20 years publishing NDNR’s Applied Naturopathic Medicine journal, I've watched "dangerous pseudoscience" become the standard of care. You may remember we were called irresponsible for publishing IV nutrient protocols. Now there's...
Homeopathy
Razi Ann Berry, Publisher We started publishing homeopathic medicine cases in 2005. Many told me I would kill our credibility, that it was “pseudoscience” or that no serious medical journal would touch it. I was told I’d never attract conventional doctors as...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Micronutrient Deficiencies and Glucose Dysregulation: Clinical Implications for Insulin Resistance
Pamela Frank, BSc, ND Learn how critical micronutrients like chromium, magnesium, and zinc impact glucose metabolism, insulin sensitivity, and the prevention of chronic conditions like Type 2 diabetes. Abstract Micronutrient deficiencies play a crucial role in the...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Integrative Restoration of Fascia Integrity: Tabasheer and Bu Zhong Yi Qi Tang
Majid Michael Sababi, ND, DC, MS, MUAc, ABDA ABSTRACT Structural disorders such as hernias, pelvic organ prolapses, fascial laxity, and connective tissue degeneration are increasingly prevalent in modern clinical practice. While often treated surgically or...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
The Integration of Naturopathic Medicine and Pharmacy: A Collaborative Approach
Emma Pollon-MacLeod, BSc., N.D. Adam Livingston, PharmD, RPh Uniting naturopathic doctors and pharmacists creates a patient-centered model that addresses chronic illness, reduces polypharmacy, and improves long-term health outcomes. This article explores how...
Optimizing Metabolic Health for Women: A Troubleshooting Approach to Insulin Resistance
Lara Briden, ND Insulin resistance goes far beyond blood sugar—affecting hormones, cardiovascular health, and long-term disease risk. An individualized, root-cause approach can restore metabolic flexibility and resilience in women. Abstract This article explores...
We were just early
Razi Ann Berry, Publisher 47% of our readers are MDs and DOs. Why are conventional doctors reading a naturopathic journal? When we started Applied Natural Medicine in 2005 ( then NDNR), our audience was almost entirely naturopathic physicians. Twenty years...
Restorative Formulations Introduces Microbiome Synergy: An Innovative Probiotic and Postbiotic Formula to Support Gut and Immune Health
MONTPELIER, VT – October 10, 2025 – Restorative Formulations, a physician-exclusive nutraceutical company known for its clinically effective, potent organic formulations, is proud to announce the launch of Microbiome Synergy, a potent, broad-spectrum probiotic and...
Biliary Hyperkinesia in Functional RUQ Pain: A Naturopathic Case Study
Lisa Jung, ND, FABNG Abstract Biliary hyperkinesia is an emerging functional gallbladder disorder characterized by elevated gallbladder ejection fraction and right upper quadrant pain in the absence of gallstones. This case study follows a 32-year-old woman with...
Klebsiella Dysbiosis and Ankylosing Spondylitis: A Naturopathic Case Study
Exploring the gut–joint connection in a patient with ankylosing spondylitis, highlighting the role of Klebsiella overgrowth, naturopathic interventions, and sustained clinical remission. Jennifer Cornell, ND Abstract Ankylosing spondylitis (AS) is a chronic...
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Featured News
AHPA Leads Legislative Response to Protect Herbal Tinctures in New Hampshire
The American Herbal Products Association (AHPA) is leading a coordinated industry response to protect the sale of alcohol-based herbal tinctures and liquid extracts in New Hampshire. The issue began when a concerned AHPA member reported that the New Hampshire Liquor...
FDA Removes Black Box Warnings from Hormone Replacement Therapy
New review of research shows benefits outweigh risks for women who start treatment within 10 years of menopause onset After more than two decades, the FDA is finally removing the black box warnings that have kept millions of women from accessing hormone replacement...





