Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...

Trending Articles
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
Resolution of Chronic Fatigue in a Patient With Post-COVID EBV Reactivation and Mold-Related Illness
Dr. Kasey Holland Hamski, ND A case illustrating the interplay between EBV reactivation, environmental mold exposure, and immune dysregulation in a patient with persistent post-viral fatigue. This case report examines chronic fatigue in a 38-year-old patient with...
Featured Article | Anxiety/Depression/Mental Health
Managing Nervous System Imbalances
PTSD in First Responders By Jannine Krause The first responder community, particularly firefighters, faces unique challenges when it comes to aging. Over the past decade, I have observed firsthand the physical and mental tolls that shift work, irregular sleep, high...
Exclusive Content | Anxiety/Depression/Mental Health
Treating Bipolar Disorder: A Review of Evidence-Informed Naturopathic Treatment Options
SAM N. CLOUTHIER, BHSC, ND Bipolar disorder is a complex illness that affects approximately 2% of the Canadian population and affects males and females in equal numbers.1 Currently, typical treatment protocols for bipolar...
Our Bugs and Our Brains
JESSICA BRANDES, ND Abstract The human microbiome exerts profound influence on neurodevelopment, stress resilience, mood regulation, and cognitive aging. Evidence shows that early-life microbial exposures shape immune and brain maturation, while disruptions—such as...
Pregnenolone & Its Metabolites
CARRIE DECKER, ND When we speak of hormones, we often think of those that play a role in mediating sexual function: estrogen, testosterone, and progesterone. These hormones come from the common base molecule of cholesterol, and all 3 derive from the mother...
Basket Weaving: How Neurasthenia Inspired the Arts & Crafts Movement and More
Jacob Schor, ND, FABNO During our time at home this past spring, I took up 2 new hobbies: chair caning and basket making. I can’t claim to be particularly accomplished at either. If you want to joke about me being a basket case,...
Managing Stress & Mood Disorders
ALYSSA DIRIENZO, ND Stress and anxiety are ubiquitous these days. Especially now – with the copious stressors associated with this pandemic, such as job loss, working from home, home-schooling, and now racial injustice as...
Social Connection: A Missing Piece of Your Treatment Plan?
ANGELA CORTAL, ND A patient, whom I’ll call Ashley, was a pleasant, friendly 31-year-old mother of 2 when she first consulted me in 2019 for migrating joint pains. A previous provider had told...
COVID-19: A Naturopathic Approach
CATHERINE CLINTON, ND As the novel SARS-CoV-2 continues to make its way across the globe, naturopathic medicine becomes more and more important. This coronavirus is new, so there is still a lot we don't know about it. We have no research to show that any of the...
Notes from the Field: December, 2019
Nature Cure Clinical Pearls Jared L. Zeff, ND, VNMI, LAc The following is a not an article prepared for a medical journal. Not every statement of fact is cited or referenced. This is a commentary on the medicine, a running set of observations about practice in the...
Archived Case Studies and Featured Content
Naturopathic Approach to Women’s Hormone Health: From Menarche to Menopause
Dr. Serena Goldstein, ND A comprehensive review of hormonal changes, mood, metabolism, and integrative strategies to support women’s health at every life stage. Short Description This article explores hormonal changes across the female lifespan—from menarche...
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
Fifteen Questions to Get Patient Commitment
Razi Berry A practical tool for doctors, practice managers, and staff to support patient decision-making and follow-through Practitioners often say they do not want to be salespeople. In practice, sales are simply a decision and a transaction between two people. One...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
By Lina Mockus, ND How the gut microbiome, systemic inflammation, and metabolic health link cardiovascular disease and prostate disorders—and what integrative care can do about it. This article explores the shared metabolic, inflammatory, and microbiome-driven...
Resolution of Exercise-Induced Asthma with Individualized Homeopathic Treatment: A Case Report
Dr. Michael Knapp, ND, DHANP A case demonstrating sustained remission of exercise-induced asthma, allergic oropharyngeal symptoms, and recurrent respiratory infections in an adolescent following constitutional homeopathic care. This case report describes the...
Arterial Plaque Regression: A Case-Based, Integrative Approach to Cardiovascular Risk Reduction
Dr. Stephen Parcell, ND A preventive cardiology case demonstrates how advanced imaging, aggressive lipid optimization, and integrative therapies can reduce coronary plaque burden in a high-risk patient. This case report examines the regression of coronary...
Closing the Care Gap in Atrial Fibrillation: An Evidenced-Based Role for Naturopathic Doctors
Dr. Olivia Greenspan, ND RN Abstract Structured risk factor modification and longitudinal lifestyle care can improve atrial fibrillation outcomes beyond rate and rhythm control alone. This article examines atrial fibrillation as a progressive, risk...
Managing Elevated Coronary Artery Calcium Scores: An Updated Clinical Guide
Dr. Joel Kahn, MD, FACC A step-by-step, evidence-informed framework for interpreting high coronary calcium CT results, refining cardiovascular risk, and implementing integrative prevention strategies. Abstract This article provides an updated, clinically...
IS TYLENOL SAFE DURING PREGNANCY?
Understanding Risk Factors, Not Causation Learn how much Tylenol pregnant women can safely take, what risk factors matter, and why glutathione status—not acetaminophen itself—determines safety during pregnancy. IN THIS ARTICLE • Key Takeaways: Tylenol Safety...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
A Somatic Approach to Stage 5 Chronic Kidney Disease: Unbinding Fear and Grief from the Renal System
Dr. Erin Hayford, ND A naturopathic case exploring how structured somatic medicine can support nervous system regulation, emotional processing, and quality of life alongside conventional care in end-stage renal disease. This case report examines the integration...
Approaching Idiopathic Neuropathy: A Naturopathic Strategy Beyond Diabetes
Dr. Jason Porter, NMD A clinical overview of diagnosing and treating non-diabetic neuropathy through root-cause evaluation, including autoimmunity, infections, biotoxin exposure, and small fiber nerve pathology. Abstract This article explores a naturopathic...
Managing Elevated Coronary Artery Calcium Scores: An Updated Clinical Guide
Dr. Joel Kahn, MD, FACC A step-by-step, evidence-informed framework for interpreting high coronary calcium CT results, refining cardiovascular risk, and implementing integrative prevention strategies. Abstract This article provides an updated, clinically...
IS TYLENOL SAFE DURING PREGNANCY?
Understanding Risk Factors, Not Causation Learn how much Tylenol pregnant women can safely take, what risk factors matter, and why glutathione status—not acetaminophen itself—determines safety during pregnancy. IN THIS ARTICLE • Key Takeaways: Tylenol Safety...
Functional Longevity Summit 2026 Sets Stage for Next Wave in Precision and Regenerative Medicine
Phoenix, Arizona — Healthcare practitioners across naturopathic, functional, regenerative, and precision medicine are gearing up for one of the most comprehensive clinical education events of the year. The 2026 Functional Longevity Summit, hosted in Phoenix from...
A Somatic Approach to Stage 5 Chronic Kidney Disease: Unbinding Fear and Grief from the Renal System
Dr. Erin Hayford, ND A naturopathic case exploring how structured somatic medicine can support nervous system regulation, emotional processing, and quality of life alongside conventional care in end-stage renal disease. This case report examines the integration...
Approaching Idiopathic Neuropathy: A Naturopathic Strategy Beyond Diabetes
Dr. Jason Porter, NMD A clinical overview of diagnosing and treating non-diabetic neuropathy through root-cause evaluation, including autoimmunity, infections, biotoxin exposure, and small fiber nerve pathology. Abstract This article explores a naturopathic...
Clinical Applications of Mind-Body Medicine: Somatic Awareness and the Wisdom of the Body
Allison Creech, M.Ed., ND An in-depth exploration of how somatic awareness, interoception, and relational neuroscience can support nervous system regulation, authenticity, and healing in clinical practice. Abstract This article examines mind-body medicine as a...
Perimenopausal Cognitive Changes (Brain Fog): A Comprehensive, Evidence-Informed Clinical Approach in a Patient with APOE4
Dr. Nicole Roberts, ND A case-based, integrative strategy for addressing brain fog, executive dysfunction, and long-term cognitive risk in perimenopausal women, including those with APOE4 genetic risk. Abstract In this case report, we see a 48-year-old female,...
Stress, Systems, and Survival: Mental Distress through an Evolutionary and Societal Lens
Dr. Leslie Solomonian, ND An exploration of mental distress as an adaptive survival response shaped by evolutionary biology, social structures, and ecological conditions—challenging symptom-focused models of mental health care. Abstract This article examines...
Borage (Borago officinalis): Botanical Ally for Courage, Self-Expression, and the Restoration of Self-Love
An integrative exploration of borage’s traditional uses, phytochemistry, and clinical applications in supporting self-compassion, stress resilience, and emotional regulation in naturopathic practice. Dr. Katelyn Mudry, ND, MSc Introduction Over the past year,...
Lavender Essential Oil and Anxiety Management: A Case Study
A case-based examination of oral lavender essential oil as a non-pharmaceutical intervention for generalized anxiety disorder in a patient seeking evidence-informed, integrative care. Dr. Jennifer Brusewitz ND Abstract This case study explores the use of a...
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Featured News
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....






