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When Rib Pain Comes from the Spine: Thoracic Radiculopathy and Targeted Platelet-Based Treatment
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The Role of Hormonal Changes in the Etiology and Treatment of Paternal Perinatal Mood and Anxiety Disorders
Approximately 1 in 10 fathers experience a perinatal mood or anxiety disorder, yet paternal PMADs remain frequently overlooked. This review explores the hormonal and psychosocial changes accompanying fatherhood and their implications for recognizing, screening, and supporting paternal mental health.
Oral Curcumin and Artesunate Protocol in Prostatic Carcinoma: Case Study Series in PSA and Pathology Outcomes
Can curcumin and artesunate play a role in integrative prostate cancer care? This two-patient case series examines PSA trajectories and pathology during an oral botanical protocol incorporating curcumin and artesunate, while highlighting potential mechanisms, iron-related adverse effects, and the need for further clinical investigation.
A New Chapter in Pain Pharmacology: Suzetrigine, NaV1.8 Inhibition, and the Future of Non-Opioid Analgesia
Suzetrigine introduces a novel mechanism for treating moderate to severe acute pain by selectively inhibiting NaV1.8 channels on peripheral nociceptors. This review examines its mechanism, clinical efficacy, safety, and potential role within multimodal naturopathic and integrative pain management.
Beyond the Tumor: A Whole-Person Approach to Prostate Cancer Active Surveillance
Active surveillance does not have to mean simply “watching and waiting.” This case follows a man with localized intermediate-risk prostate cancer over approximately 20 months, integrating conventional oncologic monitoring with serial assessment and individualized management of metabolic health, inflammation, gastrointestinal dysbiosis, environmental exposures, nutrition, and lifestyle.
Breath of Fresh Air for the Profession: Reflections from AANP 2026 in Madison
The 2026 American Association of Naturopathic Physicians (AANP) Convention arrived in Madison, Wisconsin, under unusual skies. Wildfire smoke had drifted across the region, leaving the city enveloped in smoke and fog as naturopathic physicians, students, educators,...
Featured Article | Neurology
Preventing Alzheimer’s Before It Starts: A Root-Cause Approach for Genetic ApoE4 Risk
Stephanie Yang, ND Discover how a 53-year-old woman with a strong family history of Alzheimer’s took a proactive, root-cause approach to protect her cognitive future through lifestyle, neuroprotective therapies, and metabolic support. Abstract and Introduction...
Exclusive Content | Neurology
Neuronal Hyperexcitability in PKD: Treatment Using Parenteral Therapy
2021 Student Scholarship – Second Place Case Study MATTHEW RENSHAW RUDDELL, ND LESLIE FULLER, ND Paroxysmal kinesigenic dyskinesia (PKD) is the most common paroxysmal movement disorder and is characterized by episodes of involuntary movements that are...
Amyotrophic Lateral Sclerosis: Microbiome Alterations
SAMANTHA PRYOR, ND Since this is my first article submission to NDNR, I would like to take a moment to tell you a little about myself. As I write this, I am currently employed as the last resident of the University of Bridgeport School...
The ECS at the Synapse
JAKE F. FELICE, ND, LMP This article discusses a newly discovered apoptogenic feature of the endocannabinoid system (ECS), known as retrograde transmission. It also discusses important influences of the ECS on neural plasticity, as well...
Migraine & the Microbiome
JESSICA BRANDES, ND According to the Migraine Research Foundation, 18% of women, 6% of men, and 10% of children in the United States experience migraines, resulting in 70% higher healthcare costs for families with a migraine sufferer than for non-migraine-affected...
EMF Exposure: Neuropsychiatric Effects
YASAMAN TASALLOTI, ND Since the start of the COVID-19 pandemic, there has been an increase in the utilization of technology to work, learn, and connect from home. To a great degree, this has been a welcomed solution in terms of convenience...
The ECS-Adrenal-Stress Axis
JAKE F. FELICE, ND, LMP The endocannabinoid system (ECS) responds not only to cannabis and cannabinoid molecules; it is also positively affected by diet, exercise, acupuncture, probiotics, prebiotics, acupuncture, osteopathic...
Mycotoxins & the Brain
Lauren Tessier, ND If you’ve worked with people suffering from mold and mycotoxin exposure, you are aware of the vast array of symptoms they report. It is not uncommon for people to experience a litany of cognitive symptoms, including, but not limited...
Greater than Placebo: A Critical Review of Homeopathy Research
Naturopathic Perspective Paul Theriault, BSc, ND, VNMI Discussions of homeopathy within the naturopathic profession have emerged recently, which have been predicated on the assumption that there is no evidence for homeopathy. This assumption is false. The evidence...
Archived Case Studies and Featured Content
Juvenile Idiopathic Arthritis: A Longitudinal Case of Naturopathic Care and Healing
After nearly five years without reported symptoms, a 14-year-old girl with juvenile idiopathic arthritis experienced a recurrence of joint pain, fatigue, gastrointestinal complaints, and reduced mobility. This longitudinal case examines how individualized naturopathic care, guided by the principles of healing and supported by dietary, homeopathic, and lifestyle interventions, accompanied gradual improvement in symptoms and quality of life over eight months.
Pediatric Psychosis and Catatonia: Exploring Infection-Associated Neuropsychiatric Symptoms
A previously high-functioning 10-year-old girl developed severe psychosis, catatonic features, and profound functional regression, with symptoms fluctuating for more than two years. This case examines possible infection-associated neuropsychiatric mechanisms, repeated caregiver-reported improvements during antibiotic treatment, and the patient’s eventual recovery through multidisciplinary psychiatric, medical, nutritional, and integrative care.
Babesia duncani and Pediatric Neuropsychiatric Symptoms: A Case of Delayed Diagnosis and Recovery
Following a febrile illness, a nine-year-old boy developed severe behavioral changes, anxiety, sensory disturbances, and debilitating fatigue that led to psychiatric hospitalization. This case explores the identification of Babesia duncani antibodies, a multimodal treatment approach, and the child’s subsequent improvement in neurological symptoms, emotional regulation, and daily functioning.
Pediatric ADHD and Childhood Trauma: A Trauma-Informed Naturopathic Approach
When an eight-year-old boy with previously stable ADHD developed worsening concentration, anxiety, and sleep disturbances, a trauma-informed assessment revealed a recent experience of community violence. This case explores how adverse childhood experiences can complicate pediatric ADHD presentations and how foundational naturopathic interventions targeting nutrition, sleep, and stress may complement existing behavioral and psychosocial therapies.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Brain Death Reconsidered Brain Death Reconsidered: Examining the Medical, Legal, and Ethical Debate Over Organ Donation
Heidi Klessig MD This commentary explores ongoing debates surrounding the concept of brain death, reviewing historical definitions, legal standards, published case reports, and ethical questions regarding informed consent and organ donation. Is brain death...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Brain Death Reconsidered Brain Death Reconsidered: Examining the Medical, Legal, and Ethical Debate Over Organ Donation
Heidi Klessig MD This commentary explores ongoing debates surrounding the concept of brain death, reviewing historical definitions, legal standards, published case reports, and ethical questions regarding informed consent and organ donation. Is brain death...
Root-Cause Diabetes Prevention: A Naturopathic Approach to Insulin Resistance and Metabolic Health
Jack Duke, ND Type 2 diabetes develops over years of progressive metabolic dysfunction. This article reviews the pathophysiology of insulin resistance, highlights strategies for early detection, and presents practice-based outcomes from a 12-week naturopathic...
Mental Time Reversal Breathing, Perception Biology, and Telomere-Regulated Longevity: An Integrative Neuro-Endo-Immunologic Framework
Majid Michael Sababi, ND, DC, MS, MD*, MUAc, ABDA This article explores how rhythmic breathing, mental time-reversal visualization, and psychoneuroimmunology may influence autonomic regulation, stress physiology, and telomere biology to support healthy aging...
CIRS, Water-Damaged Buildings, and Parkinson’s Disease: An Underrecognized Environmental Driver of Neurodegeneration
Eric Dorninger, ND, Lac Emerging evidence suggests that Chronic Inflammatory Response Syndrome (CIRS) caused by exposure to water-damaged buildings may contribute to neuroinflammation, Parkinsonian symptoms, and potentially modifiable pathways of...
Five Days of Oral Essential Oils Produced Symptom Relief Equal to Ten Days of Penicillin V
Physicians assessed that 58 of 67 patients on oral essential oil capsules had avoided antibiotics, and 89 percent of those patients would use the capsules again for their next sore throat. Patients with acute sore throat obtained symptom relief from five days...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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IS TYLENOL SAFE DURING PREGNANCY?
Understanding Risk Factors, Not Causation Learn how much Tylenol pregnant women can safely take, what risk factors matter, and why glutathione status—not acetaminophen itself—determines safety during pregnancy. IN THIS ARTICLE • Key Takeaways: Tylenol Safety...
Quantum Energy Field and Its Effects on Cellular ATP Production Rates in Human Cells
Author: Robert Sheaff, PhD, and Ian Mitchell Abstract This study investigated whether quantum field exposure generated by Quantum Upgrade based on Leela Quantum technology, influences adenosine triphosphate (ATP) production in human cell lines. This double-blind...
Georgia State Brain Researchers Draw Cellular Blueprint for How We Think, Feel
A new study from experts with Georgia State University has achieved a long-standing goal in neuroscience: showing how the brain’s smallest components build the systems that shape thought, emotion and behavior, by demonstrating how specific cell types, chemical...
Featured News
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Paris to Host Landmark Global Gathering for Naturopathic Medicine in 2026
10th Integrative & Naturopathic Medicine World Congress & Expo Returns for Its Milestone 10th Edition Paris — July 10–11, 2026 — The global stage is set for one of the most influential events in integrative healthcare as the 10th Integrative &...
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