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Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
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Table of Contents | 2006 | February
February 2006 | Oncology
When Drugs Meet Nutraceuticals: Cytochrome P450 Interactions.............................>>cover Tina Kaczor, ND Abnormal Cell Growth in Light of Naturopathic Philosophy................................>> bottom of cover Arlan Cage, ND, MSOM, MS Vulvar...
Salicylates in Salix, Populus and Betula
Eric Yarnell, ND, RH(AHG) These three medicinal trees all contain significant quantities of salicylates, on the order of 3%-10% by dry weight in bark and leaves. Many ancient texts, including the Ebers papyrus (approximately 5,100 years old), recommend these and...
When Drugs Meet Nutraceuticals:Cytochrome P450 Interactions
With the current estimates of one in every two men and one in every three women being diagnosed with cancer in their lifetime, chances are every naturopathic doctor will see patients with this disease. Many of these patients will be receiving conventional treatments,...
The Use of Aromatic Therapies In the Treatment of Cancer
Shaida Sina, ND Cancer is a complex disease state that requires a holistic approach to treatment. Aromatic therapies may provide valuable adjunctive treatment options. Some of the areas which are currently being explored in relation to aromatic therapies include tumor...
Cytochrome P450 Interactions
Tina Kaczor, ND With the current estimates of one in every two men and one in every three women being diagnosed with cancer in their lifetime, chances are every naturopathic doctor will see patients with this disease. Many of these patients will be receiving...
Abnormal Cell Growth in Light of Naturopathic Philosophy
Arlan Cage, ND, MSOM, MS Cancer conjures up fearful images for most people: relatives or loved ones wasting away in a slow, painful process of suffering and increasing loss of body functions, finally ending in a death which many will describe as "merciful" since it...
Vulvar Intraepithelial Neoplasia (VIN)
Deanna Berman, ND I have been seeing more and more women with what is generally termed “Vulvar Dystrophies”. These are noncancerous conditions that affect the skin around the outer area of the vagina, the vulva. The vulva consists of the labia majora, labia minora,...
Taxus brevifolia (Pacific yew) and Cancer
Eric Yarnell, ND, RD(AHG) In 1963 the National Cancer Institute found that extracts of Taxus brevifolia (Pacific yew) bark were active in vitro against cancer cells. A sample was sent to researcher Monroe Wall, PhD, in North Carolina to follow up. Wall and associates...
Eye of the Hurricane: Surviving Cancer, Treating Cancer
Ken Weizer, ND Having been on this journey of cancer since 1989, I have had many wonderful and many terrible experiences. This journey has taken me from being a Hollywood film maker with cancer, to being an Oregon naturopathic physician who treats people with cancer....
Agaricus blazei Murrill: Immune System Ally; Cancer Foe
Ronald Steriti, NMD, PHD For thousands of years, mushrooms have been used as food and medicine. The Greek physician, Hippocrates (460 BC—377 BC), considered the “Father of Medicine,” mentions fungi in his writings for use when treating chronic kidney disease. Although...
Website for Cosmetic Ingredient’s Toxicity
Mitch Kennedy, ND Did you know the government cannot mandate safety studies of cosmetics? Only 11 percent of the 10,500 ingredients FDA has documented in products have been assessed for safety by the cosmetic industry's review panel. The exemplary environmental...
Acute Effects of a Fungal Volatile Compound
Mitch Kennedy, ND Species of molds that grow in ventilation systems, water damaged areas of buildings, or areas exposed to flood waters will discharge volatile compounds during their lifecycle. Researchers at the University Hospital in Uppsala, Sweden studied the...
Equal Parts Naturopathy, Love, and Determination: Cancer Prevention and Treatment
Satya Ambrose, L. AC, ND I have so many extraordinary stories that have come out of working with cancer patients. Most of them have survived. A few have not, but each of their lives touched me greatly. Each has been my teacher, showing me the preciousness of our time...
Archived Case Studies and Featured Content
From Chemistry to Clinical Application: Essential Oils as Multitarget Therapeutics for Microbiome Balance Across Three Mucosal Systems
Essential oils contain complex compounds with antimicrobial, antibiofilm, anti-inflammatory, and other biological activities. Dr. Sarah LoBisco explores how essential oil chemistry, formulation, and route of administration inform targeted applications for microbiome balance across the gastrointestinal, respiratory, and urinary systems.
Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
Chemotherapy-induced peripheral neuropathy can persist long after cancer treatment, affecting pain, balance, function, and quality of life. This review examines evidence-informed strategies for CIPN, including Mediterranean-style nutrition, exercise, acupuncture, duloxetine, cryotherapy and compression, while identifying commonly used supplements that lack benefit or may worsen neuropathy.
Care Beyond the Cure: An Integrative Approach to Palliative Care
Palliative care is not about abandoning treatment or losing hope—it is about adding another layer of support. This article explores an integrative, interdisciplinary approach that introduces symptom management, quality-of-life support, advance care planning, and emotional and spiritual care early in the course of serious illness.
When Rib Pain Comes from the Spine: Thoracic Radiculopathy and Targeted Platelet-Based Treatment
After 2 years of persistent right costal-margin pain, negative visceral evaluations, and unsuccessful conservative treatment, neurodynamic testing and targeted examination localized a suspected T10 radicular source with additional thoracic articular and peripheral neural involvement. A single image-guided, multi-structure platelet-based intervention was followed by substantial and durable improvement in pain and function.
Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report
Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Custom Publishing
From Chemistry to Clinical Application: Essential Oils as Multitarget Therapeutics for Microbiome Balance Across Three Mucosal Systems
Essential oils contain complex compounds with antimicrobial, antibiofilm, anti-inflammatory, and other biological activities. Dr. Sarah LoBisco explores how essential oil chemistry, formulation, and route of administration inform targeted applications for microbiome balance across the gastrointestinal, respiratory, and urinary systems.
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Quantum Energy Effects on Cell Recovery Rates
Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...
Featured News
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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