By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
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Table of Contents | 2025
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Short Description: Recurrent C. difficile infections pose a significant...
The Fertility Factor No One Talks About: Men’s Energetic Health
Dr. Laura Chan, ND, L.Ac. While male fertility is usually framed around sperm quality and lifestyle, emotional suppression and energetic stagnation may play a critical role in sexual vitality, reproductive wellness, and overall health. Abstract This article...
Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
Mind, Immunity & Male Fertility: A Psychoneuroimmunological View of Male Reproductive Health
Dr. Nicole Cain Exploring how chronic stress, inflammation, and the gut-brain-hormone connection influence sperm quality—and how integrative, mind-body interventions can restore reproductive vitality in men. Abstract This article examines male infertility...
Targeting Mitochondrial Function for Upstream Steroidogenesis and Adrenal Health
Chris D. Meletis, N.D. A clinical framework for restoring adrenal and gonadal hormone balance by supporting mitochondrial bioenergetics, antioxidant capacity, and adaptogenic stress resilience—upstream of testosterone, cortisol, and thyroid therapies. Abstract...
Recognizing Paternal Postpartum Depression: An Underaddressed Component of Perinatal Mental Health
Alexsia Priolo Understanding the signs, risk factors, screening tools, and family-wide impacts of paternal postpartum depression—and how clinicians can better support fathers throughout the perinatal period. Abstract This article highlights paternal postpartum...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
Lina Mockus, ND Emerging research reveals that gut-derived inflammation, microbial metabolites, and metabolic dysfunction link intestinal health to cardiovascular disease and prostate disorders—highlighting key opportunities for naturopathic, lifestyle, and...
Men’s Health & Compounding: A Pharmacist’s Perspective
Dr. Fatimah Hamade, PharmD Understanding Male Hypogonadism, Hormone Balancing, and the Role of Personalized Compounding in Optimizing Testosterone Therapy Abstract This article reviews the clinical foundations of male hypogonadism, testosterone evaluation, and...
The Most EXTREME Prostate Cancer Case I Have Seen in 23 Years of Practice…and What I Learned
Phranq D. Tamburri, NMD Abstract: A rare Gleason 10 prostate cancer in an 80‑year‑old veteran with a persistently low PSA challenges conventional risk models, highlights the limits of PSA‑based screening, and illustrates how active surveillance, patient personality,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
The Role of Histamine and Serotonin in Upper GI Motility: Clinical Insights from Three Case Reviews
Bradley Bush, ND Exploring how neuroimmune imbalances between histamine and serotonin contribute to dysmotility, GERD, and bloating—and how targeted integrative strategies can improve outcomes. Abstract This article reviews the interplay between histamine and...
Metabolite-Informed Estrogen-Pathway Modulation for Adult Female Acne Remission: A Systems-Based Case Report
Anna Kolomitseva, ND A case study illustrating how individualized hormone-metabolism targeting, dietary modulation, and circadian stabilization achieved sustained acne remission after oral-contraceptive discontinuation and brief testosterone exposure. Abstract Adult...
Phytoandrogens in Pine Pollen: Emerging Evidence for Anabolic and Hormone Health
Saeid Mushtagh, ND Abstract Pine pollen Song Hua Fen (松花粉) has long been celebrated in Traditional Chinese Medicine (TCM) for its ability to nourish Yang Qi, the Heart, Lungs, resolve dampness and wind, with various attributes of health and longevity.1,2 It is now...
Clinically Proven Natural Support for Autoimmune Rheumatic Conditions
Authors: Devin Miles, ND & Elizabeth Sutherland, ND Emerging research highlights how botanicals such as berberine, cordyceps, rehmannia, and rosmarinic acid can modulate immune pathways and reduce inflammation in autoimmune diseases like lupus and rheumatoid...
Archived Case Studies and Featured Content
Chemotherapy-Induced Peripheral Neuropathy: An Evidence-Based Guide for Naturopathic Physicians
Chemotherapy-induced peripheral neuropathy can persist long after cancer treatment, affecting pain, balance, function, and quality of life. This review examines evidence-informed strategies for CIPN, including Mediterranean-style nutrition, exercise, acupuncture, duloxetine, cryotherapy and compression, while identifying commonly used supplements that lack benefit or may worsen neuropathy.
Care Beyond the Cure: An Integrative Approach to Palliative Care
Palliative care is not about abandoning treatment or losing hope—it is about adding another layer of support. This article explores an integrative, interdisciplinary approach that introduces symptom management, quality-of-life support, advance care planning, and emotional and spiritual care early in the course of serious illness.
When Rib Pain Comes from the Spine: Thoracic Radiculopathy and Targeted Platelet-Based Treatment
After 2 years of persistent right costal-margin pain, negative visceral evaluations, and unsuccessful conservative treatment, neurodynamic testing and targeted examination localized a suspected T10 radicular source with additional thoracic articular and peripheral neural involvement. A single image-guided, multi-structure platelet-based intervention was followed by substantial and durable improvement in pain and function.
When Pain Was Where Shame Lived: Abdominal Pain and the Mind-Body Connection
After imaging failed to reveal a significant structural explanation for severe recurrent abdominal pain, attention shifted toward chronic stress, body image, and the mind-body connection. This case explores the patient’s experience with craniosacral therapy and integrative care as her relationship with her body changed and her abdominal pain ultimately resolved.
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Micronized Progesterone in Advanced Endometrial Cancer: Two Integrative Naturopathic Oncology Case Reports
Could micronized progesterone have a broader role in supportive care for advanced endometrial cancer? These two case reports describe its integration primarily for sleep support in women with high-risk disease, alongside naturopathic and conventional oncology therapies, and discuss its potential hormonal and anticancer relevance as an area for further investigation.
Optimizing Preoperative Nutrition in Cancer Surgery: The Role of Tumor Type, Glycemic Load, and Hydration
Preoperative nutrition in cancer surgery is not a one-size-fits-all intervention. This article examines how tumor metabolism and malnutrition risk can guide protein intake, carbohydrate selection, immuno-nutrition, pancreatic enzyme support, and hydration strategies to better prepare oncology patients for surgery and recovery.
Mebendazole and Fenbendazole for Cancer: Examining the Evidence, Risks, and Potential Harms
Mebendazole and fenbendazole have attracted attention as unconventional cancer therapies, but how strong is the clinical evidence supporting their use? This critical review examines proposed anticancer mechanisms, reported outcomes, potential neurotoxicity and drug resistance, and the importance of informed risk-benefit discussions with cancer patients.
Integrative Supportive Quality of Life Care in Classic Hodgkin Lymphoma Following COVID-19 Infection: A Case Report
This case report describes the treatment and recovery of a 45-year-old woman with Stage II Classic Hodgkin lymphoma diagnosed following COVID-19 infection. Alongside standard chemotherapy and immunotherapy, a structured integrative supportive care plan—including intravenous nutrient therapy, nutritional optimization, and restorative modalities—was implemented to reduce treatment-related toxicities, support immune resilience, and enhance long-term quality of life.
The Infection Nobody Thought to Look For: Post-Infection Autoimmune Conditions
Jaquel Patterson, ND, MBA, FMCP-M Emerging research links pathogens such as Epstein-Barr virus, SARS-CoV-2, Lyme disease, and other infections to autoimmune disease through molecular mimicry, chronic inflammation, and immune...
Paresthesias, White Matter Hyperintensities, and Possible Preclinical Multiple Sclerosis: The Emerging Role of Environmental Mycotoxin Screening
Saied Mushtagh, ND Patients with paresthesias and nonspecific white matter hyperintensities often present diagnostic challenges when imaging is inconclusive for multiple sclerosis. This review examines differential diagnosis, neurologic risk stratification, and...
Rethinking the Thyroid Panel: Thyroid Antibodies, T3, and Brain Fog
Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Custom Publishing
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Quantum Energy Effects on Cell Recovery Rates
Robert Sheaff, PhD, and Ian Mitchell This study investigated whether quantum field exposure generated by Leela Quantum Bloc Technology influences cell recovery rates in human cell lines. A series of double-blind experiments were conducted using Human Dermal...
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Featured News
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Naturopathic Medical Education: A Comprehensive Curriculum
Colleen Huber, NMD April 9 2026 The following is a comparison of my conventional medical education and subsequent naturopathic medical education. I wrote this in 2015, and now update it in April 2026, only with updated curriculum links and screenshots from the various...
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