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Medication-Induced Kidney Injury: Mechanisms, Risk Factors, and Prevention
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Trending Articles
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Naturopathic Therapeutic Order in Cancer Care: A Framework for Integrative Oncology
How can naturopathic therapies be thoughtfully integrated across the continuum of cancer care? This article applies the Naturopathic Therapeutic Order to oncology, illustrating through a breast cancer case how foundational care, self-healing strategies, system support, symptom management, and conventional treatments can be organized within a comprehensive integrative approach.
Topical Calendula Oil for Cancer Pain: An Opioid-Sparing Analgesic Approach in Recurrent Anal Squamous Cell Carcinoma
Can topical calendula help manage severe cancer-related anal pain? This case report describes a rapid, sustained reduction in pain following topical Calendula officinalis oil in a patient with recurrent anal squamous cell carcinoma, highlighting its potential as a well-tolerated, opioid-sparing adjunct worthy of further clinical investigation.
Viscum album for High-Grade Cervical Dysplasia: A Novel Direct-Application Protocol
This case report describes a novel protocol using direct cervical application of Viscum album in a patient with persistent high-grade cervical dysplasia who was awaiting LEEP. Although causality cannot be established, treatment was well tolerated and was followed by an unexpected absence of residual dysplasia on the excised specimen, supporting further investigation of localized Viscum album therapy as a potential adjunctive approach.
Featured Article | Gastrointestinal
Interpreting the Unusual: Functional Insights from Atypical Breath Test Patterns
Dr. Bradley Bush, ND Unlock hidden patterns in hydrogen and methane testing—learn how atypical breath test results reveal valuable functional insights for gut health and individualized treatment strategies. Abstract Breath testing is a cornerstone diagnostic tool for...
Exclusive Content | Gastrointestinal
SIBO in a Young Woman: A Cure with Botanical Medicine
Vis Medicatrix Naturae Matthew Strickland, ND Abstract Small intestinal bacterial overgrowth (SIBO) is increasingly recognized as both an underdiagnosed condition and a contributor to irritable bowel syndrome (IBS). This case study describes a 19-year-old female who...
NPLEX: What Board Certification Actually Means
Practice Building Joy Stevens, ND, JD, PE Congratulations! You passed NPLEX. No, you are not board-certified. NPLEX Exam The Naturopathic Physician Licensing Examination (“NPLEX”) is a 2-part examination, the purpose of which is to ensure a licensure candidate...
Dialing Up the Vis, Part 1
The Vital Conversation James Sensenig, ND This is the first of a new series of articles in NDNR based on transcripts of The Vital Conversation. The conversations occurred on Wednesdays for several years and were hosted by Jim Sensenig, ND, and other senior vitalists....
James Sensenig, ND: In Memoriam; December 1, 2019
JARED ZEFF, with a little help from my friends James Sensenig (“call me Jim”) was an intelligence officer in the US Army during the Viet Nam War. They picked the most capable people for that assignment. In 1974, he enrolled in the National College of Naturopathic...
Acute Food Poisoning: Possible Trigger for a Variety of Chronic GI Disorders
Tolle Causam Steven Sandberg-Lewis, ND, DHANP Abstract Acute gastroenteritis is increasingly recognized as a potential initiating event in the development of chronic gastrointestinal (GI) disorders, including celiac disease, inflammatory bowel disease (IBD), and...
Anemia of Chronic Disease: Treatment with Lipoic Acid, Resveratrol, & Curcumin
Naturopathic Perspective Quinn Rivet ND Anemia of chronic disease (ACD), also known as anemia of inflammation, is typically characterized by a microcytic or normocytic, normochromic anemia with low reticulocytes, along with possible mildly low hematocrit, hemoglobin,...
Clinical Focus – GI Health
Naturopathic Urgent Care Rebecca Miller, NMD There are few (if any) urgent care or emergency medicine physicians in this country that are trained to approach an acutely ill patient with the guiding philosophy of Tolle causam, ie, treat the whole person. And yet, if...
A Complex Case of Recurrent SIBO: Involvement of an Underlying Cryptic Infection
Tolle Totum Melanie Keller, NDMichael D. Erdman, MBBS Although the origins of irritable bowel syndrome (IBS) were once thought to be mostly psychogenic, we now know that the pathogenesis of IBS is multifactorial. This paradigm shift may be due in part to the fact that...
Archived Case Studies and Featured Content
When Rib Pain Comes from the Spine: Thoracic Radiculopathy and Targeted Platelet-Based Treatment
After 2 years of persistent right costal-margin pain, negative visceral evaluations, and unsuccessful conservative treatment, neurodynamic testing and targeted examination localized a suspected T10 radicular source with additional thoracic articular and peripheral neural involvement. A single image-guided, multi-structure platelet-based intervention was followed by substantial and durable improvement in pain and function.
When Pain Was Where Shame Lived: Abdominal Pain and the Mind-Body Connection
After imaging failed to reveal a significant structural explanation for severe recurrent abdominal pain, attention shifted toward chronic stress, body image, and the mind-body connection. This case explores the patient’s experience with craniosacral therapy and integrative care as her relationship with her body changed and her abdominal pain ultimately resolved.
Medication-Induced Kidney Injury: Mechanisms, Risk Factors, and Prevention
Medications may account for an estimated 20% of community- and hospital-acquired acute kidney injury, with risk amplified by CKD, older age, chronic disease, dehydration, and polypharmacy. This review examines the major mechanisms of drug-induced nephrotoxicity and practical strategies for medication review, hydration, renal monitoring, and prevention.
Low Testosterone and Cardiovascular Disease: Risk Marker, Mediator, or Both?
Low testosterone is consistently associated with adverse cardiovascular outcomes, but whether it is a cause of vascular disease or a marker of underlying metabolic and inflammatory dysfunction remains unresolved. This review examines the epidemiology, vascular mechanisms, hypertension and atherosclerosis data, TRAVERSE findings, and the cardiovascular implications of TRT-induced erythrocytosis.
When Menopausal Symptoms Aren’t Menopause: Lessons from a Case of Pituitary Hypophysitis and the Value of Comprehensive Endocrine Assessment
Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Short Description: Recurrent C. difficile infections pose a significant...
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
The Silent Male Infertility Epidemic: How Men Can Protect & Restore Their Fertility
Dr. Samuel Madeira, N.M.D. Infertility affects about 180 million people worldwide and at least 15% of couples in the United States alone. The far-too-often overlooked factor in fertility medicine today is the male contribution, accounting for the cause of 30-50% of...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Short Description: Recurrent C. difficile infections pose a significant...
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
The Silent Male Infertility Epidemic: How Men Can Protect & Restore Their Fertility
Dr. Samuel Madeira, N.M.D. Infertility affects about 180 million people worldwide and at least 15% of couples in the United States alone. The far-too-often overlooked factor in fertility medicine today is the male contribution, accounting for the cause of 30-50% of...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
From PCOS to PMOS: What the Name Change Means for Your Practice
Dr. Jaclyn Smeaton, ND A clinical review of the landmark renaming of PCOS to PMOS and why this shift reframes the condition as a whole-body endocrine and metabolic disorder requiring broader assessment and long-term care. This article explores the recent...
Collaborative Fertility Care: How Naturopathic Doctors and Nurse Practitioners Can Expand Integrative Treatment Options
Dr. Nora Pope ND, FCP A clinical exploration of how collaborative ND–NP care can bridge prescribing limitations, integrate restorative fertility strategies, and expand access to individualized reproductive treatment. This article examines the clinical value of...
Resolving Fatigue, Food Sensitivities, and PMS in a 38-Year-Old Female: A Gut–HPA Axis Case Report
Dr. Brian Lamoreux, ND, MA, LPCC A clinical case exploring the interconnected roles of HPA axis dysfunction, gut dysbiosis, food reactivity, and stress physiology in new-onset fatigue and premenstrual symptoms. This case report follows a 38-year-old woman with...
Progesterone Resistance and Implantation Failure: An Integrative Approach to Endometrial Receptivity
Dr. BreAnna Guan, ND A whole-person exploration of how inflammation, endocrine disruptors, metabolic dysfunction, gut dysbiosis, and stress may impair progesterone signaling and compromise fertility. This article examines progesterone resistance as an...
Age-Related Fertility Decline: Improving Oocyte Quality Through Integrative Naturopathic Care
Dr. Shannon Sinsheimer, ND A clinical review of mitochondrial dysfunction, oxidative stress, and evidence-informed nutritional strategies to support oocyte maturation, embryo quality, and successful conception in advanced reproductive age. This article explores...
Custom Publishing
Actionable Habits That Help You Lose Weight and Stay Healthy
Simone McFarlane Achieving sustainable weight loss isn’t about dramatic diets or fleeting willpower; it’s about forming habits that support your body’s natural balance and energy. Wellness-focused changes that are consistent, manageable, and grounded in how...
Naturopathic Applications of Mild Hyperthermia
Applications in Practice John H. Furlong, ND Naturopathic medicine sits at a crossroads. As we progress through the 21st century, we have an opportunity to re-assert our unique leadership place in natural medicine. We can challenge ourselves to build on our...
Featured News
Allergy Research News Release
RAZI BERRY Allergy Research Group Announces Peer-Reviewed Publication Advancing Thyroid and Endocrine Integration Science Collaborative research led by ARG’s Medical Affairs and Scientific Advisory Board reinforces the company’s commitment to thyroid category...
Strive Compounding Pharmacy Files Federal Antitrust Lawsuit Against Eli Lilly and Novo Nordisk
ARCADIA TALLMAN Strive Compounding Pharmacy has filed a federal antitrust lawsuit against Eli Lilly and Novo Nordisk, alleging a coordinated effort to suppress competition and restrict patient access to lawful compounded GLP-1 medications. The complaint, filed on...
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