Dr. Todd Maderis, ND Exploring immune dysregulation, viral reactivation, mitochondrial impairment, and treatment implications in post-EBV fatigue syndromes. Abstract This article examines the role of Epstein–Barr virus (EBV) reactivation and immune exhaustion in the...
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Intravenous Phosphatidylcholine in Severe Refractory Mast Cell Activation Syndrome: A Case Report
Melanie Stein, ND Clinical improvement in treatment-refractory MCAS with normal conventional biomarkers and profound oral intolerance through membrane lipid therapy. This case report describes a 34-year-old woman with severe, treatment-refractory mast cell...
PANS, PANDAS, and the Expanding Landscape of Post-Infectious Neuroimmune Syndromes Across the Lifespan
Dr. Carolyn Mukai, ND, Dr. Lynn Klassen, ND, Dr. Ece Toprak, ND Expanding recognition of infection-triggered neuroinflammation in children, adolescents, and adults—and the evolving role of integrative immune regulation. Abstract: This clinical commentary...
From Wheelchair to Garden: Restoring Function in Complex Post-Infectious Illness Through Foundational Naturopathic Care
Dr. Jenny Tufenkian, ND A phased naturopathic approach addressing foundational digestive stabilization, EBV reactivation, neuroinflammation, and autonomic dysfunction in a severely disabled patient. Abstract Background: Myalgic encephalomyelitis/chronic fatigue...
A Case of Recurring Acute Viral Meningitis
Deborah Frances RN, ND A 14-year journey from “unexplained headaches” to confirmed HSV-2 meningitis, highlighting how accurate diagnosis, antiviral botanicals, and individualized homeopathic prescribing can control severe neurologic symptoms and cardiac...
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Male Factor Infertility: Naturopathic Case Insights and Lifestyle-Based Interventions to Improve Sperm Health
Khivan Oberoi, ND Exploring the clinical complexities of male infertility and the impact of lifestyle, environmental, and naturopathic interventions on reproductive outcomes — with real-world case examples that demonstrate how integrative care can optimize...
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Treating Chronic Pain: Reasons to Use a Top-Down System
Naturopathic Perspective MARK HEISIG, ND Pain is an interesting phenomenon within the brain and as a part of the human experience. And it's important to emphasize the human "experience" component, because pain is just that – an experience....
Charles: A Case Study
Joseph Kellerstein, DC, ND Charles, a man in his mid-50s, presented to my office in early 2018. He was tall, lean, and appeared to be in good physical condition. “My wife has noticed a substantial curvature of my erect penis,”...
Naturopathic Medical Education: Contrary Imperatives
Education David J. Schleich, PhD What distinguishes the medicine of the past twenty-five years is not that its practitioners are equipped with an arsenal of antibiotics and antiseptics, but that they are furnished with a comprehensive and unprecedented understanding...
Castor Oil: Magic or Myth (Part 2)
Vis Medicatrix Naturae Marisol Teijeiro, ND Like any good legend, the story of castor oil throughout the ages is one of ebbing and flowing, but mainly one of adapting into the common medical practices of the time. From the glory years in ethnobotanical and cultural...
Notes from the Field: August, 2019
Nature Cure Clinical Pearls Jared L. Zeff, ND, VMNI, LAc The following is a not an article prepared for a medical journal. Rather, this is a commentary on the medicine, a running set of observations about practice in the field. It’s not meant to be a peer-reviewed...
Beyond Saw Palmetto: The Complexity of Benign Prostatic Hyperplasia
Tolle Totum Eric Yarnell, ND, RH (AHG) The common condition benign prostatic hyperplasia (BPH) remains relatively poorly understood clinically. There is much room for improvement, including a long way to go beyond just providing Serenoa repens (saw palmetto) and...
CaP Update 2019: Is MRI Imaging Replacing Biopsy?
Docere Phranq D. Tamburri, NMD Over the past decade, as has been documented in my previous NDNR articles, my practice has specialized in the proper use of prostate imaging for concerned patients with an elevated prostate-specific antigen (PSA) who want to avoid a...
Male Infertility: Successful Results Achieved By Antioxidants
Tolle Causam Chris D. Meletis, ND According to the World Health Organization (WHO)’s International Committee for Monitoring Assisted Reproductive Technology, infertility is a reproductive system disease characterized by failure to achieve clinical pregnancy after 1...
Archived Case Studies and Featured Content
Spring 2026 Conference: Advancing Care in the Era of Progressive Disease
Orchestrated by one of the leading authorities in naturopathic and integrative medicine, Dr. Paul Anderson will be presenting the 19th International hybrid CME conference for Advanced Applications in Medical Practice (AAMP) during May 15th to 17th in Scottsdale,...
Sequencing in Multi-Mycotoxin Illness: A Case Report on Binding Capacity, Immune Modulation, Membrane Support, and Glutathione Therapy
Dr. Autumn Frandsen, ND Abstract This case describes a 71-year-old female presenting with acute-onset neuropsychiatric and systemic symptoms following relocation to a new office environment. Laboratory evaluation revealed elevated complement component C4a and...
Glymphatic Detoxification: The Missing Link in Brain Health and Environmental Toxin Clearance
Dr. Millie (Millennia) Lytle ND, MPH, CNS Abstract Why optimizing glymphatic drainage is essential for cognitive resilience, detoxification, and the prevention of neurodegenerative and systemic disease. This clinical commentary explores the glymphatic system as a...
East Meets West: A Springtime Approach to Liver Detoxification
Dr. Heather Tynan, ND, DACM, Lac Abstract Bridging Traditional Chinese Medicine and Western physiology to support liver function, detoxification pathways, and systemic balance during the spring season. This article explores a seasonal, integrative approach to...
The First Health Food Store in America Was Opened by a Naturopathic Doctor in 1896
In 1896, a 24-year-old German immigrant named Benedict Lust opened a small store in New York City. He called it a “Kneipp store,” named after Father Sebastian Kneipp, the German priest whose water cure treatments had saved Lust’s life after conventional doctors gave...
Three Endocrine Axes Share One Energy Budget for Stress Resilience
Three Endocrine Axes Share One Energy Budget for Stress Resilience Mitochondrial reserve capacity constrains the HPA, thyroid, and gonadal systems simultaneously, determining whether stress responses stay adaptive or consolidate into chronic dysfunction. When a...
AANP and AANMC Urge Naturopathic Community to Act: Proposed Federal Rule Threatens ND Student Loan Access and Future Workforce
Washington, DC — The American Association of Naturopathic Physicians (AANP) and the Association of Accredited Naturopathic Medical Colleges (AANMC) are calling on naturopathic physicians, students, patients, and all allies to urgently submit public comments opposing a...
Physician’s Choice Awards and Summit – Interview with Joah Santos
Physician's Choice Awards and Summit – Interview with Joah Santos Host: Razi BerryGuest: Joah Santos (Expert on Tribalism, Marketing Strategist for Fortune 500s, NGOs, and Governments) In this episode, Razi Berry sits down with Joah Santos, a renowned expert on...
The Night Sky Changed Emotional State in 2.5 Minutes
Night sky photos activated all 6 dimensions of awe, increased positive emotion, and restored mental focus in under 3 minutes. People Who Looked at the Night Sky Felt Vastly Different Within Minutes Photographs of deep space and starry night skies activated all 6...
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Eight Communities You Never Thought of That Can Be a Goldmine for Finding New Patients
Advancing Public Health Through Community Alignment Valuing self-reliance and freedom, certain enthusiast groups are naturally drawn to holistic, naturopathic, and integrative care because it aligns with their ethos of personal autonomy and preparedness. These are...
Environmental Stressors Now Cause 1 in 5 Cardiovascular Deaths
ARCADIA TALLMAN Air pollution, noise, chemicals, and climate events cause an estimated 4 to 6 million of the 20 million annual cardiovascular deaths worldwide, exceeding many traditional risk factors, according to a joint ESC, ACC, AHA, and WHF statement. Four Major...
Air Pollution Disrupted Menstrual Cycles in Premenopausal Women
Common traffic and industrial exhaust gases disrupted estrogen and progesterone cycling, damaged ovarian tissue, and shortened menstrual intervals in premenopausal women, yet environmental exposure history remains absent from standard reproductive health evaluations....
Thymosin Alpha-1 Restored Immune Function Across Five Organ Systems
ARCADIA TALLMAN The thymus peptide upregulated 1,198 genes tied to energy metabolism, DNA repair, and cell cycle regulation. The Thymus Shrinks With Age and Takes Immune Function With It The thymus gland loses 95% of its immature immune cells with age, and the peptide...
Fluoxetine During Development Damaged Hearing and the Brainstem
ARCADIA TALLMAN Fluoxetine exposure during early auditory development drove 91 gene expression changes in the brainstem, reduced the stability of mature neural circuits, and left lasting hair-cell damage in the inner ear. Fluoxetine Changed the Developing Auditory...
Eight Communities You Never Thought of That Can Be a Goldmine for Finding New Patients
Advancing Public Health Through Community Alignment Valuing self-reliance and freedom, certain enthusiast groups are naturally drawn to holistic, naturopathic, and integrative care because it aligns with their ethos of personal autonomy and preparedness. These are...
Overcoming Objections to Pay Cash for Doctor’s Visits: Scripts Your Staff Can Use
Razi Berry Handling Objections Handling objections to paying cash for doctor’s visits can be a delicate task. It requires empathy, clear communication, and an understanding of the patient's concerns. Here are some effective scripts that your staff can use to address...
Fifteen Questions to Get Patient Commitment
Razi Berry A practical tool for doctors, practice managers, and staff to support patient decision-making and follow-through Practitioners often say they do not want to be salespeople. In practice, sales are simply a decision and a transaction between two people. One...
The Gut-Heart-Prostate Connection: The Link between Intestinal, Cardiovascular, and Prostate Health in Men
By Lina Mockus, ND How the gut microbiome, systemic inflammation, and metabolic health link cardiovascular disease and prostate disorders—and what integrative care can do about it. This article explores the shared metabolic, inflammatory, and microbiome-driven...
Arterial Plaque Regression: A Case-Based, Integrative Approach to Cardiovascular Risk Reduction
Dr. Stephen Parcell, ND A preventive cardiology case demonstrates how advanced imaging, aggressive lipid optimization, and integrative therapies can reduce coronary plaque burden in a high-risk patient. This case report examines the regression of coronary...
Resolution of Exercise-Induced Asthma with Individualized Homeopathic Treatment: A Case Report
Dr. Michael Knapp, ND, DHANP A case demonstrating sustained remission of exercise-induced asthma, allergic oropharyngeal symptoms, and recurrent respiratory infections in an adolescent following constitutional homeopathic care. This case report describes the...
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New Pain Signalling Switch Discovered by Tulane‑Led Team May Transform Treatment
A team of scientists from Tulane University and eight partner institutions has identified a previously unknown way that nerve cells communicate to trigger pain. In a study published in Science on November 20 2025, the researchers show that nerve cells can release an...
Digoxin Prescribed to Some Patients Can Lead To Higher Death Risk
According to a study published Aug. 11 in The Journal of the American College of Cardiology, doctors need to use caution when prescribing digoxin to patients with atrial fibrillation as it can cause debilitating strokes. The print version will appear Aug. 19. Digoxin,...
The Current Status of Psilocybin Research: Depression, Anxiety & Trauma
By Pam Conboy Part 3 (a. & b.) of this series will provide an overview of the current status of psilocybin research in a variety of conditions. Today’s article will focus on its efficacy in depression, anxiety, and trauma. Breakthrough Therapy (2018;2019) ...
Featured News
Strive Compounding Pharmacy Files Federal Antitrust Lawsuit Against Eli Lilly and Novo Nordisk
ARCADIA TALLMAN Strive Compounding Pharmacy has filed a federal antitrust lawsuit against Eli Lilly and Novo Nordisk, alleging a coordinated effort to suppress competition and restrict patient access to lawful compounded GLP-1 medications. The complaint, filed on...
Three Endocrine Axes Share One Energy Budget for Stress Resilience
Three Endocrine Axes Share One Energy Budget for Stress Resilience Mitochondrial reserve capacity constrains the HPA, thyroid, and gonadal systems simultaneously, determining whether stress responses stay adaptive or consolidate into chronic dysfunction. When a...









