Andrea Sulyok, ND Can patients with Hashimoto's thyroiditis experience persistent cognitive symptoms despite normal thyroid hormone levels? This article examines the potential roles of thyroid antibodies, tissue-level T3 activity, and objective brain...
Trending Articles
Low-Dose Naltrexone (LDN) as an Adjunctive Therapy for Autoimmunity and Chronic Inflammation: A Collaborative Case Report
Fatima Hamade, PharmD, BCACP This case report explores the use of compounded low-dose naltrexone (LDN) as an adjunctive therapy for persistent autoimmune symptoms, highlighting its proposed immunomodulatory mechanisms, individualized dosing strategies, and the...
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Brain Death Reconsidered Brain Death Reconsidered: Examining the Medical, Legal, and Ethical Debate Over Organ Donation
Heidi Klessig MD This commentary explores ongoing debates surrounding the concept of brain death, reviewing historical definitions, legal standards, published case reports, and ethical questions regarding informed consent and organ donation. Is brain death...
Featured Article | NDNR Issues
Understanding Preeclampsia
How to Reduce Risk in Pregnancy and Prevent Future Cardiovascular Disease By Alexsia Priolo Introduction Pregnancy places significant physiologic stress on the cardiovascular system, prompting structural and hemodynamic changes to manage increased blood volume and...
Exclusive Content | NDNR Issues
Rewiring Fear and Worry
A Holistic Approach to Conquering Anxiety in the Female Patient By Jonathan E. Prousky, ND, MSc, MA Introduction This paper investigates the prevalence, key hormonal contributors, and integrative treatment strategies for anxiety disorders in women, highlighting the...
Migraines & Menopause
Two Case Studies By Jillian Finker, ND Introduction After two decades of practicing naturopathic medicine, I have observed that advancements in allopathic migraine treatment remain limited. While a few newer medications may be effective for specific individuals, most...
Ayurvedic Strategies for Low Testosterone
Restoring Balance Through Digestion, Dosha Regulation, and Targeted Interventions By Dr. Virender Sodhi MD (Ayurveda), ND In recent years, the conversation around men’s health, particularly testosterone levels, has gained significant attention. While modern medicine...
Is Low-Dose Prescribing a Possible New Naturopathic Modality?
Men’s Fertility Restored with Lisinopril By Nora Jane Pope, FCP This article examines the off-label use of low-dose lisinopril for treating idiopathic male infertility based on a compelling Nigerian study. It explores how lose-dose prescribing could be a naturopathic...
Inhibiting Myostatin To Promote Muscle Mass in Men
Chris D. Meletis, N.D. With age, the sails of our sailboat become deflated unless we take a proactive approach to fight the statistical trends. This is never more true than with the loss of muscle mass. After age 30, people lose about 3% to 5% of their muscle mass...
Clinical Uses for DHEA Supplementation in Male Patients
Optimizing hormonal health and preventing age-related decline By Briana Cain, ND Discover the clinical applications of DHEA supplementation in male patients, focusing on its benefits for cardiovascular health, bone density, cognitive function, and hormonal...
Mind Mechanics: Exploring Brain Network Dynamics in Men for Focus, Performance, and Mood
By: Dr. Nicole Cain, ND, MA Recent neuroscience advances reveal that intriguing differences in brain network dynamics between cisgender men and women, significantly impact cognitive performance and emotional regulation. This article explores three key neural networks...
Identifying and Overcoming Obstacles to Men’s Health: A Provider’s Guide
By Lillea Hartwell, ND, RH The gap between men’s health and women’s health continues to grow. In fact, “According to most health studies, men generally have a shorter life expectancy than women.”1 Getting to the root cause of why seems to be a multi-layered issue....
Archived Case Studies and Featured Content
How to Get the Most from Your Cancer Doctor Visits: A Guide for Patients and Survivors
Cancer care can be complex and overwhelming, but preparation can make medical appointments more productive and less stressful. This practical checklist offers 18 strategies to help patients communicate effectively with providers, organize their care, explore treatment options, and build a collaborative medical “dream team.”
Botanical Immunomodulation for Pancreatic Neoplasia: An Integrative Medicine Case Report
Can botanical immunomodulation play a supportive role in patients with pancreatic neoplasia? This case report describes the clinical course of a patient who declined surgery, chemotherapy, and radiation and pursued a physician-directed botanical regimen alongside nutrition, exercise, meditation, and other lifestyle measures, with subsequent imaging reportedly demonstrating stabilization followed by reduction in lesion size.
Serial ctDNA in High-Grade Serous Ovarian Carcinoma: Bridging Naturopathic and Conventional Oncology Care
Serial ctDNA testing provided an evolving molecular picture of advanced ovarian cancer, helping inform treatment decisions as the patient moved between naturopathic and conventional care. This case illustrates how multiple liquid-biopsy platforms can complement CA-125 while adding molecular detail relevant to treatment response and progression.
The Future of Precision Oncology: Molecular Profiling and Personalized Treatment in Metastatic Colorectal Cancer
How can precision oncology move beyond simply matching a mutation to a drug? Through a case of KRAS G13D metastatic colorectal cancer, this article demonstrates how serial molecular profiling can help clinicians interpret tumor evolution and integrate genomics with metabolism, nutrition, immune-directed strategies, natural medicines, repurposed pharmaceuticals, and conventional oncology.
The Missing Question: How Occupational Heavy Metal Exposure Contributed to Severe Testosterone Deficiency in a Young Male
Glenn B. Gero, ND, DSc, M.E.S., R.H. (AHG), EndoANP Kareem Kandil, MD, ND A case study demonstrating how a simple occupational history uncovered chronic heavy metal exposure as a likely contributor to severe hypogonadism, highlighting the critical role of...
Reduction of Thyroid Antibodies with Tirzepatide in Hashimoto’s Thyroiditis: A Metabolic-Immune Case Report
Dr. Valerie Gettings, NMD A case report exploring how low-dose tirzepatide improved insulin resistance, thyroid function, and thyroid autoantibody levels in a patient with Hashimoto’s thyroiditis, highlighting the emerging role of metabolic therapies in...
16-Hydroxyestrone, Enterohepatic Recirculation, and Dysmenorrhea: Personalizing Hormone Care Through Estrogen Metabolite Testing
Dr. Liz Bartman, ND A case-based exploration of how urinary estrogen metabolites can reveal hidden patterns of estrogen recirculation, gut-liver dysfunction, and hormone clearance that contribute to menstrual pain and heavy bleeding. This case report examines a...
Nigella sativa: The Ancient Herbal Remedy Supporting Thyroid Resilience in Hashimoto’s Thyroiditis
Lillea Hartwell, ND A comprehensive review of Nigella sativa seed oil, its active constituents, safety profile, pharmacology, and emerging clinical evidence for supporting immune regulation and thyroid function in Hashimoto’s thyroiditis. This monograph reviews...
When Menopausal Symptoms Aren’t Menopause: Lessons from a Case of Pituitary Hypophysitis and the Value of Comprehensive Endocrine Assessment
Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Migraines and Menopause: Two Case Studies
By Jillian Finker, ND Explore how naturopathic approaches effectively address hormonal migraines in menopausal women through real-life patient case studies. Summary: This article explores two case studies of women suffering from migraines during menopause. It...
Chronic Clostridioides difficile Infections: Two Naturopathic Case Studies
Exploring two complex cases of recurrent C. difficile infections unresponsive to antibiotics and FMT, and how naturopathic interventions supported long-term remission and restored quality of life. Short Description: Recurrent C. difficile infections pose a significant...
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
The Silent Male Infertility Epidemic: How Men Can Protect & Restore Their Fertility
Dr. Samuel Madeira, N.M.D. Infertility affects about 180 million people worldwide and at least 15% of couples in the United States alone. The far-too-often overlooked factor in fertility medicine today is the male contribution, accounting for the cause of 30-50% of...
Co-Prescribing Probiotics with Antibiotics: The Case for Omni-Biotic AB 10
Omni-Biotic Human clinical trials demonstrate that functionally targeted Omni-Biotic AB 10 prevents diarrhea, reduces C. difficile risk, and eliminates multidrug resistant organism colonization in the gut. Introduction Antibiotics are among the most...
From PCOS to PMOS: What the Name Change Means for Your Practice
Dr. Jaclyn Smeaton, ND A clinical review of the landmark renaming of PCOS to PMOS and why this shift reframes the condition as a whole-body endocrine and metabolic disorder requiring broader assessment and long-term care. This article explores the recent...
Custom Publishing
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Quantum Fields and Frequency Medicine
Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow within integrative and naturopathic...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Featured News
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...









