Adrianne M. Cook, ND, FABNE A case report illustrating how fatigue, weight gain, brain fog, metabolic dysfunction, and vasomotor symptoms initially attributed to menopause revealed underlying hypopituitarism, central adrenal insufficiency, and secondary...

Trending Articles
Relative Energy Deficiency in Sport (RED-S): When “Eat Less, Move More” Backfires in Active Adults
Ben Alter, MA, ND How chronic low energy availability disrupts metabolism, hormones, recovery, immune function, and performance—and why recreationally active individuals may be especially vulnerable. This article explores Relative Energy Deficiency in Sport (RED-S), a...
Vitamin D Beyond Bone Health: Emerging Roles in Immunity, Metabolic Health, PMOS, and Disease Prevention
Dr. Daniella Perri, ND From widespread deficiency to VDR signaling across tissues, this review synthesizes evidence on how vitamin D shapes immunity, infection severity (including COVID-19), tumor biology, uterine fibroids, metabolic syndrome, and PMOS—and outlines...
Liver-Centered Model of Midline Adiposity & MASLD
by Majid Michael Sababi, ND, DC, MS, MUAc, ABDA Discover how hepatic steatosis, insulin resistance, and liver dysfunction contribute to visceral fat accumulation, and explore evidence-informed assessment and treatment strategies that integrate modern hepatology with...
Recurrent Pregnancy Loss Assessment: An Integrative Approach
Dr. Juline Savaya, ND Beyond “Unexplained” Recurrent Pregnancy Loss: An Integrative Approach to Immune, Hormonal, Thrombophilic, and Male-Factor Assessment Pregnancy loss occurs in approximately 15% to 20% of recognized pregnancies, though the true prevalence...
Featured Article | Products and Services
Integrations: our newest product category for connecting (even more) dots between science and symptoms
NeuroScience has always focused on addressing the science behind symptoms. This remains our approach to healthcare because we believe everything is connected. A single symptom doesn’t have a single resolution, and bodily systems like the nervous or immune systems work...
Exclusive Content | Products and Services
AllergoSan USA’s Omni-Biotic Stress Release Recognized as Nutraingredients USA Probiotic of the Year
PORT CHESTER, NY AllergoSan USA’s Omni-Biotic Stress Release psychobiotic was recognized as Nutraingredients USA Probiotic of the Year. Focusing on true innovation, long-term market success and cutting-edge research, the NutraIngredients-USA Awards honor the best and...
ECS Nutraceuticals Group LLC Receives NSF International’s Good Manufacturing Practice Certification
HAUPPAUGUE, NY - ECS Nutraceuticals Group LLC, the manufacturer of ECS Therapeutics® premier healthcare-exclusive hemp CBD brand and other private label brands, was recently added to NSF International’s NSF/ANSI 455-2 Dietary Supplements Good Manufacturing Practice...
ELISA/ACT® Biotechnologies Introduces COVID Vax LRA Panel
Test now available to identify delayed immune hypersensitivity to the components in COVID-19 vaccines currently available in the U.S. Sterling, VA – Over 200 million COVID-19 vaccine doses have been administered in the US, however a sizeable percentage of Americans...
Lifestyle Matrix Resource Center Announces Revamped Clinical Program to Address Gut Health Challenges
WOODSTOCK, IL—Lifestyle Matrix Resource Center (LMRC), a hub of clinical tools and resources for functional medicine practitioners, is thrilled to announce the newly revamped Pillars of GI Health Program. As new research continues to build around functional medicine...
MegaMycoBalance
MegaMycoBalance is a powerful natural formula that supports healthy yeast and fungal balance in the body.Yeasts are a natural part of a healthy and well-balanced gut microbiome. However, they can quickly grow out of control if this careful balance is thrown off by...
Hilma Introduces Gas Relief
Hilma, a natural remedies brand known for its clinically researched alternatives to OTC brands, introduced a new Gas Relief product on February 23rd. Hilma’s Gas Relief is a capsule that relieves gas and bloating with a blend of soothing herbs. Created by Hilma’s...
Nature’s One Continues to Commit to Purity and Sound Nutritional Science
Lewis Center, Ohio – For over 20 years, Nature’s One has worked diligently to find and sourceonly the purest ingredients for its formulas, nutritional beverages, and now our recentlyintroduced infant cereal product. Independent laboratory testing conducted by Pure...
ECS Therapeutics™ offers CE webinar on therapeutic potential of topical cannabinoids, plus introduces three new products
Hauppauge, NY – ECS Therapeutics™, the leading provider of a healthcare practitioner-exclusive line of CBD products, is committed to the continuing education of healthcare professionals. Offering a free CE credit (approved for General, Pharmacy, or Pain), ECS...
Archived Case Studies and Featured Content
ClarityTx Launches Clinical Decision-Support Platform for Integrative Medicine
ClarityTx, a healthcare technology company, announced the launch of its clinical decision-support platform designed specifically for integrative and functional medicine practitioners. Created by a multidisciplinary team of clinicians, the platform helps practitioners...
Fibromyalgia and Chronic Fatigue Syndrome: A Mitochondrial Perspective on Recovery and Root Causes
Wiet van Helmond, Classical Homeopath Drawing from decades of clinical experience and a representative case study, this article explores how mitochondrial dysfunction, chronic inflammation, post-viral illness, psychosocial stress, and individualized homeopathic...
Brain Death Reconsidered Brain Death Reconsidered: Examining the Medical, Legal, and Ethical Debate Over Organ Donation
Heidi Klessig MD This commentary explores ongoing debates surrounding the concept of brain death, reviewing historical definitions, legal standards, published case reports, and ethical questions regarding informed consent and organ donation. Is brain death...
Root-Cause Diabetes Prevention: A Naturopathic Approach to Insulin Resistance and Metabolic Health
Jack Duke, ND Type 2 diabetes develops over years of progressive metabolic dysfunction. This article reviews the pathophysiology of insulin resistance, highlights strategies for early detection, and presents practice-based outcomes from a 12-week naturopathic...
Collaborative Fertility Care: How Naturopathic Doctors and Nurse Practitioners Can Expand Integrative Treatment Options
Dr. Nora Pope ND, FCP A clinical exploration of how collaborative ND–NP care can bridge prescribing limitations, integrate restorative fertility strategies, and expand access to individualized reproductive treatment. This article examines the clinical value of...
Resolving Fatigue, Food Sensitivities, and PMS in a 38-Year-Old Female: A Gut–HPA Axis Case Report
Dr. Brian Lamoreux, ND, MA, LPCC A clinical case exploring the interconnected roles of HPA axis dysfunction, gut dysbiosis, food reactivity, and stress physiology in new-onset fatigue and premenstrual symptoms. This case report follows a 38-year-old woman with...
Progesterone Resistance and Implantation Failure: An Integrative Approach to Endometrial Receptivity
Dr. BreAnna Guan, ND A whole-person exploration of how inflammation, endocrine disruptors, metabolic dysfunction, gut dysbiosis, and stress may impair progesterone signaling and compromise fertility. This article examines progesterone resistance as an...
Age-Related Fertility Decline: Improving Oocyte Quality Through Integrative Naturopathic Care
Dr. Shannon Sinsheimer, ND A clinical review of mitochondrial dysfunction, oxidative stress, and evidence-informed nutritional strategies to support oocyte maturation, embryo quality, and successful conception in advanced reproductive age. This article explores...
Restoration of Cycle Regularity and Healthy Pregnancy in a 41-Year-Old Woman with Diminished Ovarian Reserve: A Naturopathic Case Report
Dr. Aumatma Simmons, ND A root-cause fertility case exploring hormonal optimization, vaginal microbiome restoration, luteal phase support, and individualized naturopathic care in advanced reproductive age. This case report details the successful restoration of...
Natural Conception Following Ovarian PRP and Integrative Naturopathic Fertility Care: Two Case Reports
Dr. Emmalyn Pratt, ND Two fertility case reports exploring the potential role of ovarian platelet-rich plasma (PRP) alongside naturopathic interventions in women with diminished ovarian reserve, recurrent pregnancy loss, and failed assisted reproductive...
From Protocols to Precision: Using Organic Acid Testing to Personalize IVF Preparation
Dr. Shannon Iselin, ND How metabolomic assessment of oxidative stress, mitochondrial function, and nutrient sufficiency may help optimize reproductive outcomes beyond conventional fertility markers. This article explores the potential role of organic acid...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...
Rethinking Mental Health Treatment: The Clinical Case for Natural Neurotransmitter Support
Dr. Jaquel Patterson, ND, Dr. Elizabeth Sutherland, ND, and Dr. Devin Miles, ND A clinical review of evidence-based botanical and nutritional compounds that support serotonergic, dopaminergic, GABAergic, and stress-response pathways in...
Ovulation-Triggered Migraine: A Naturopathic Clinical Case Study
By Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A 38-year-old female with predictable mid-cycle and late luteal migraines achieved relief through an integrative approach combining nutrition, botanicals, supplementation, and conventional care. This case study...
Natural Conception Following Ovarian PRP and Integrative Naturopathic Fertility Care: Two Case Reports
Dr. Emmalyn Pratt, ND Two fertility case reports exploring the potential role of ovarian platelet-rich plasma (PRP) alongside naturopathic interventions in women with diminished ovarian reserve, recurrent pregnancy loss, and failed assisted reproductive...
From Protocols to Precision: Using Organic Acid Testing to Personalize IVF Preparation
Dr. Shannon Iselin, ND How metabolomic assessment of oxidative stress, mitochondrial function, and nutrient sufficiency may help optimize reproductive outcomes beyond conventional fertility markers. This article explores the potential role of organic acid...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...
Rethinking Mental Health Treatment: The Clinical Case for Natural Neurotransmitter Support
Dr. Jaquel Patterson, ND, Dr. Elizabeth Sutherland, ND, and Dr. Devin Miles, ND A clinical review of evidence-based botanical and nutritional compounds that support serotonergic, dopaminergic, GABAergic, and stress-response pathways in...
Ovulation-Triggered Migraine: A Naturopathic Clinical Case Study
By Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A 38-year-old female with predictable mid-cycle and late luteal migraines achieved relief through an integrative approach combining nutrition, botanicals, supplementation, and conventional care. This case study...
Mediterranean Diet and Olive Oil in Women’s Health: Clinical Evidence and Applications
By Dr. Artemis Morris, ND From ancestral kitchen wisdom to modern research, exploring how the Mediterranean diet supports hormonal health, fertility, pregnancy, menopause, and longevity. This article examines the Mediterranean diet as a clinically validated,...
Lactational Mastitis: Naturopathic and Integrative Treatment Protocols
by Dr. Daniella Perri, ND Understanding the causes, symptoms, and evidence-based conventional and alternative therapies — including probiotics, allicin, and therapeutic ultrasound — to support recovery and prevent recurrence. This article explores the...
Naturopathic Dementia Prevention: Clinical Strategies for Neurodegeneration
Dr. Majid Michael Sababi, ND, DC, MS, MUAc, ABDA A practical framework addressing injury load, neuroplastic repair, and multi-domain interventions including lifestyle, diet, sleep, stress, and targeted nutraceutical strategies. This article presents a...
Estrogen Metabolism and the Gut Microbiome: Clinical Strategies for Hormone Detoxification
Dr. Holly Lucille, RN, ND A comprehensive review of liver detoxification phases, the estrobolome, and lifestyle, nutritional, and botanical strategies to support healthy estrogen balance. This article explores estrogen metabolism through a whole-person lens,...
Integrative Treatment of Anxiety and Depression: A Clinical Case Report
by Dr. Christina Bjorndal, ND A six-year case study demonstrating the role of nutrition, lifestyle, and psychotherapeutic interventions in resolving complex mental health conditions. This case report details the successful resolution of anxiety, depression,...
Custom Publishing
Hyperbaric Oxygen Therapy in Sports Medicine: Clinical Applications in Concussion and Musculoskeletal Injury
Joseph Thomas, MD, MBA, Fellow of Metabolic and Nutritional Medicine In collaboration with Oxygen Health Systems Abstract Hyperbaric oxygen therapy has gained traction as an adjunct in sports medicine, particularly in concussion management and musculoskeletal injury....
Quantum Fields and Frequency Medicine
Quantum Fields and Frequency Medicine A Conversation with Philipp Samor von Holtzendorff Fehling on Remote Quantum Technology and Human Performance Interest in frequency medicine and subtle energy technologies continues to grow within integrative and naturopathic...
Increased Intracellular NAD+ Levels via Oral Supplementation With a Novel Liposomal Delivery Method: A Non-Randomized Crossover Study
Blair E, Miller A, McDonald R. Introduction: NAD+ is a critical coenzyme for cellular energy production, DNA repair, and sirtuin activity, with levels known to decline with age. While oral NAD+ supplementation is proposed for healthy aging benefits, its efficacy in...
Featured News
The 2026 AzureWellness Summit
Building a Community of Practitioners to Inspire Healthier Families June 22–26 Five Day Virtual Event of Education, Insight, and Whole-Person Wellness AzureWell is pleased to announce the Azure Wellness Summit, a free five-day virtual event taking place June...
NWHSU Launches New Doctor of Clinical Nutrition in Functional & Integrative Nutrition
Northwestern Health Sciences University (NWHSU) is proud to announce the launch of its new Doctor of Clinical Nutrition (DCN) in Functional and Integrative Nutrition– a practice-focused doctoral degree designed for nutrition and healthcare professionals ready to...









